遺伝子発現バンク(GEO)目次バージョン:2013-04-06English page
NCBI Gene Expression Omnibus (GEO) に登録されているデータを、測定技術と材料の属性に基づいて整理しました。
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データ単位 : [ データセット / サンプル / プラットフォーム ] 単位の説明>> <<説明を隠す
データセット  : 研究・目的ごとにまとめられた発現データの集合 (発現データマトリクス)
サンプル  : 測定に附された生体試料
プラットフォーム : 発現定量のための測定プロトコル
各タブ内に表示される数値は、そのタブ分類に属するデータ数です。
  ヒト
(502,421)
  霊長
(4,928)
  齧歯
(181,106)
  哺乳
(16,260)
  脊椎
(18,263)
  無脊椎
(37,338)
  植物
(91,454)
  バクテリア
(39,082)
  ウィルス
(1,266)
  ファージ
(101)
  未分類
(5,242)
  すべて
(898,944)
 
  SAGE NlaIII
(0)
  SAGE RsaI
(0)
  SAGE Sau3A
(0)
  MPSS
(0)
  GeneChip
(7,355)
  タイリングアレイ
(676)
  cDNAアレイ
(10,532)
  オリゴアレイ
(19,682)
  ビーズアレイ
(0)
  タンパク質アレイ
(0)
  抗体アレイ
(0)
  RT-PCR
(51)
  HT-Seq
(729)
  その他
(57)
  すべて
(39,082)
 
 
(89)
 
(312)
  結合
(123)
  生殖
(41)
 
(90)
  消化
(193)
 
(64)
 
(199)
 
(5)
  分泌
(69)
  胎児
(4)
  地上構造
(0)
  若い地上構造
(0)
 
(0)
  成長点
(0)
  花・生殖
(0)
  種子・果実
(0)
  混合
(59)
  分類不能
(18,434)
  すべて
(19,682)
 
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サンプルID タイトル データ数 登録機関 登録日 プラットフォーム サンプルタイプ 生物種 臓器分類 分類の根拠
黒字の強調部分が臓器分類時に用いたキーワードになります。
1 GSM113980 H.influenzae_90-1 4,971 University of Oklahoma Health Sciences Center 2006-06-12 [オリゴアレイ] Nimblegen Haemophilus influenzae Rd KW20 array 2236 (GPL3870) RNA Haemophilus influenzae Rd KW20
Haemophilus influenzae Rd KW20
骨格筋 H. influenzae Rd KW20 grown in iron and heme deplete media for 90 minutes, replicate 1
2 GSM114029 H.influenzae_90-2 4,971 University of Oklahoma Health Sciences Center 2006-06-12 [オリゴアレイ] Nimblegen Haemophilus influenzae Rd KW20 array 2236 (GPL3870) RNA Haemophilus influenzae Rd KW20
Haemophilus influenzae Rd KW20
骨格筋 H. influenzae Rd KW20 grown in iron and heme deplete media for 90 minutes, replicate 2
3 GSM114030 H.influenzae_90-3 4,971 University of Oklahoma Health Sciences Center 2006-06-12 [オリゴアレイ] Nimblegen Haemophilus influenzae Rd KW20 array 2236 (GPL3870) RNA Haemophilus influenzae Rd KW20
Haemophilus influenzae Rd KW20
骨格筋 H. influenzae Rd KW20 grown in iron and heme deplete media for 90 minutes, replicate 3
4 GSM114031 H.influenzae_110-1 4,971 University of Oklahoma Health Sciences Center 2006-06-12 [オリゴアレイ] Nimblegen Haemophilus influenzae Rd KW20 array 2236 (GPL3870) RNA Haemophilus influenzae Rd KW20
Haemophilus influenzae Rd KW20
骨格筋 H. influenzae Rd KW20 grown in iron and heme deplete media for 90 minutes, then supplemented with Fe and Heme, replicate 1
5 GSM114032 H.influenzae_110-2 4,971 University of Oklahoma Health Sciences Center 2006-06-12 [オリゴアレイ] Nimblegen Haemophilus influenzae Rd KW20 array 2236 (GPL3870) RNA Haemophilus influenzae Rd KW20
Haemophilus influenzae Rd KW20
骨格筋 H. influenzae Rd KW20 grown in iron and heme deplete media for 90 minutes, then supplemented with Fe and Heme, replicate 2
6 GSM114033 H.influenzae_110-3 4,971 University of Oklahoma Health Sciences Center 2006-06-12 [オリゴアレイ] Nimblegen Haemophilus influenzae Rd KW20 array 2236 (GPL3870) RNA Haemophilus influenzae Rd KW20
Haemophilus influenzae Rd KW20
骨格筋 H. influenzae Rd KW20 grown in iron and heme deplete media for 90 minutes, then supplemented with Fe and Heme, replicate 3
7 GSM201546 HI_119601_HK295Cy5_KW20Cy3_new_MDS.mev.refIsIA.out 32,448 The J. Craig Venter Institute 2007-06-15 [オリゴアレイ] JCVI PFGRC Haemophilus influenzae 32K vt1 array designed primarily based on strain HK12 [FULL_FEATURE_LAYOUT] (GPL5328) genomic インフルエンザ菌(Haemophilus influenzae)
Haemophilus influenzae
骨格筋 Haemophilus influenzae(Hi) is a gram-negative rod shaped bacterium that lives symbiotically in the upper respiratory tract of humans. Capsulated Hi, as well as non-capsulated strains are known to cause a number of significant infections. Recognizing and understanding the links between the phenotypic traits and the genetic background has paramount epidemiological and clinical importance. To date, a panoply of microbiological and molecular biology tools have been developed and utilized by researchers aimed at identifying the evolutionary links among strains and isolates. Comparative genomic hybridization (CGH) has been shown to be a useful tool for screening strains for their genetic content. However, there is a major limitation when CGH is conducted on a microarray based on a single reference genome. CGH results report which genes are present or absent relative to the genome. Hence the information about novel genetic content that the query strain possesses remains obscure. We report here the construction of the first Hi pan-genome microarray representing ca. 4600 features by 70-mers. In addition to those from the Rd strain, new features originate from the unfinished genome sequences present in NCBI database and from our novel gene discovery project efforts using strain HK1212. Genomes of 20 strains belonging to different phylogenetic lineages were screened for their gene loss and gain utilizing the species microarray.
8 GSM201575 HI_119602_HK1220Cy5_KW20Cy3_new_MDS.mev.refIsIA.out 32,448 The J. Craig Venter Institute 2007-06-15 [オリゴアレイ] JCVI PFGRC Haemophilus influenzae 32K vt1 array designed primarily based on strain HK12 [FULL_FEATURE_LAYOUT] (GPL5328) genomic インフルエンザ菌(Haemophilus influenzae)
Haemophilus influenzae
骨格筋 Haemophilus influenzae(Hi) is a gram-negative rod shaped bacterium that lives symbiotically in the upper respiratory tract of humans. Capsulated Hi, as well as non-capsulated strains are known to cause a number of significant infections. Recognizing and understanding the links between the phenotypic traits and the genetic background has paramount epidemiological and clinical importance. To date, a panoply of microbiological and molecular biology tools have been developed and utilized by researchers aimed at identifying the evolutionary links among strains and isolates. Comparative genomic hybridization (CGH) has been shown to be a useful tool for screening strains for their genetic content. However, there is a major limitation when CGH is conducted on a microarray based on a single reference genome. CGH results report which genes are present or absent relative to the genome. Hence the information about novel genetic content that the query strain possesses remains obscure. We report here the construction of the first Hi pan-genome microarray representing ca. 4600 features by 70-mers. In addition to those from the Rd strain, new features originate from the unfinished genome sequences present in NCBI database and from our novel gene discovery project efforts using strain HK1212. Genomes of 20 strains belonging to different phylogenetic lineages were screened for their gene loss and gain utilizing the species microarray.
9 GSM201576 HI_119604_HK1214Cy5_KW20Cy3_new_MDS.mev.refIsIA.out 32,448 The J. Craig Venter Institute 2007-06-15 [オリゴアレイ] JCVI PFGRC Haemophilus influenzae 32K vt1 array designed primarily based on strain HK12 [FULL_FEATURE_LAYOUT] (GPL5328) genomic インフルエンザ菌(Haemophilus influenzae)
Haemophilus influenzae
骨格筋 Haemophilus influenzae(Hi) is a gram-negative rod shaped bacterium that lives symbiotically in the upper respiratory tract of humans. Capsulated Hi, as well as non-capsulated strains are known to cause a number of significant infections. Recognizing and understanding the links between the phenotypic traits and the genetic background has paramount epidemiological and clinical importance. To date, a panoply of microbiological and molecular biology tools have been developed and utilized by researchers aimed at identifying the evolutionary links among strains and isolates. Comparative genomic hybridization (CGH) has been shown to be a useful tool for screening strains for their genetic content. However, there is a major limitation when CGH is conducted on a microarray based on a single reference genome. CGH results report which genes are present or absent relative to the genome. Hence the information about novel genetic content that the query strain possesses remains obscure. We report here the construction of the first Hi pan-genome microarray representing ca. 4600 features by 70-mers. In addition to those from the Rd strain, new features originate from the unfinished genome sequences present in NCBI database and from our novel gene discovery project efforts using strain HK1212. Genomes of 20 strains belonging to different phylogenetic lineages were screened for their gene loss and gain utilizing the species microarray.
10 GSM201577 HI_119609_HK1141Cy5_KW20Cy3_new_MDS.mev.refIsIA.out 32,448 The J. Craig Venter Institute 2007-06-15 [オリゴアレイ] JCVI PFGRC Haemophilus influenzae 32K vt1 array designed primarily based on strain HK12 [FULL_FEATURE_LAYOUT] (GPL5328) genomic インフルエンザ菌(Haemophilus influenzae)
Haemophilus influenzae
骨格筋 Haemophilus influenzae(Hi) is a gram-negative rod shaped bacterium that lives symbiotically in the upper respiratory tract of humans. Capsulated Hi, as well as non-capsulated strains are known to cause a number of significant infections. Recognizing and understanding the links between the phenotypic traits and the genetic background has paramount epidemiological and clinical importance. To date, a panoply of microbiological and molecular biology tools have been developed and utilized by researchers aimed at identifying the evolutionary links among strains and isolates. Comparative genomic hybridization (CGH) has been shown to be a useful tool for screening strains for their genetic content. However, there is a major limitation when CGH is conducted on a microarray based on a single reference genome. CGH results report which genes are present or absent relative to the genome. Hence the information about novel genetic content that the query strain possesses remains obscure. We report here the construction of the first Hi pan-genome microarray representing ca. 4600 features by 70-mers. In addition to those from the Rd strain, new features originate from the unfinished genome sequences present in NCBI database and from our novel gene discovery project efforts using strain HK1212. Genomes of 20 strains belonging to different phylogenetic lineages were screened for their gene loss and gain utilizing the species microarray.
11 GSM201578 HI_119739_HK635Cy5_KW20Cy3_new_MDS.mev.refIsIA.out 32,448 The J. Craig Venter Institute 2007-06-15 [オリゴアレイ] JCVI PFGRC Haemophilus influenzae 32K vt1 array designed primarily based on strain HK12 [FULL_FEATURE_LAYOUT] (GPL5328) genomic インフルエンザ菌(Haemophilus influenzae)
Haemophilus influenzae
骨格筋 Haemophilus influenzae(Hi) is a gram-negative rod shaped bacterium that lives symbiotically in the upper respiratory tract of humans. Capsulated Hi, as well as non-capsulated strains are known to cause a number of significant infections. Recognizing and understanding the links between the phenotypic traits and the genetic background has paramount epidemiological and clinical importance. To date, a panoply of microbiological and molecular biology tools have been developed and utilized by researchers aimed at identifying the evolutionary links among strains and isolates. Comparative genomic hybridization (CGH) has been shown to be a useful tool for screening strains for their genetic content. However, there is a major limitation when CGH is conducted on a microarray based on a single reference genome. CGH results report which genes are present or absent relative to the genome. Hence the information about novel genetic content that the query strain possesses remains obscure. We report here the construction of the first Hi pan-genome microarray representing ca. 4600 features by 70-mers. In addition to those from the Rd strain, new features originate from the unfinished genome sequences present in NCBI database and from our novel gene discovery project efforts using strain HK1212. Genomes of 20 strains belonging to different phylogenetic lineages were screened for their gene loss and gain utilizing the species microarray.
12 GSM201579 HI_119740_HK389Cy5_KW20Cy3_new_MDS.mev.refIsIA.out 32,448 The J. Craig Venter Institute 2007-06-15 [オリゴアレイ] JCVI PFGRC Haemophilus influenzae 32K vt1 array designed primarily based on strain HK12 [FULL_FEATURE_LAYOUT] (GPL5328) genomic インフルエンザ菌(Haemophilus influenzae)
Haemophilus influenzae
骨格筋 Haemophilus influenzae(Hi) is a gram-negative rod shaped bacterium that lives symbiotically in the upper respiratory tract of humans. Capsulated Hi, as well as non-capsulated strains are known to cause a number of significant infections. Recognizing and understanding the links between the phenotypic traits and the genetic background has paramount epidemiological and clinical importance. To date, a panoply of microbiological and molecular biology tools have been developed and utilized by researchers aimed at identifying the evolutionary links among strains and isolates. Comparative genomic hybridization (CGH) has been shown to be a useful tool for screening strains for their genetic content. However, there is a major limitation when CGH is conducted on a microarray based on a single reference genome. CGH results report which genes are present or absent relative to the genome. Hence the information about novel genetic content that the query strain possesses remains obscure. We report here the construction of the first Hi pan-genome microarray representing ca. 4600 features by 70-mers. In addition to those from the Rd strain, new features originate from the unfinished genome sequences present in NCBI database and from our novel gene discovery project efforts using strain HK1212. Genomes of 20 strains belonging to different phylogenetic lineages were screened for their gene loss and gain utilizing the species microarray.
13 GSM201580 HI_119741_HK2067Cy5_KW20Cy3_new_MDS.mev.refIsIA.out 32,448 The J. Craig Venter Institute 2007-06-15 [オリゴアレイ] JCVI PFGRC Haemophilus influenzae 32K vt1 array designed primarily based on strain HK12 [FULL_FEATURE_LAYOUT] (GPL5328) genomic インフルエンザ菌(Haemophilus influenzae)
Haemophilus influenzae
骨格筋 Haemophilus influenzae(Hi) is a gram-negative rod shaped bacterium that lives symbiotically in the upper respiratory tract of humans. Capsulated Hi, as well as non-capsulated strains are known to cause a number of significant infections. Recognizing and understanding the links between the phenotypic traits and the genetic background has paramount epidemiological and clinical importance. To date, a panoply of microbiological and molecular biology tools have been developed and utilized by researchers aimed at identifying the evolutionary links among strains and isolates. Comparative genomic hybridization (CGH) has been shown to be a useful tool for screening strains for their genetic content. However, there is a major limitation when CGH is conducted on a microarray based on a single reference genome. CGH results report which genes are present or absent relative to the genome. Hence the information about novel genetic content that the query strain possesses remains obscure. We report here the construction of the first Hi pan-genome microarray representing ca. 4600 features by 70-mers. In addition to those from the Rd strain, new features originate from the unfinished genome sequences present in NCBI database and from our novel gene discovery project efforts using strain HK1212. Genomes of 20 strains belonging to different phylogenetic lineages were screened for their gene loss and gain utilizing the species microarray.
14 GSM201581 HI_119742_HK1219.2Cy5_KW20Cy3_new_MDS.mev.refIsIA.out 32,448 The J. Craig Venter Institute 2007-06-15 [オリゴアレイ] JCVI PFGRC Haemophilus influenzae 32K vt1 array designed primarily based on strain HK12 [FULL_FEATURE_LAYOUT] (GPL5328) genomic インフルエンザ菌(Haemophilus influenzae)
Haemophilus influenzae
骨格筋 Haemophilus influenzae(Hi) is a gram-negative rod shaped bacterium that lives symbiotically in the upper respiratory tract of humans. Capsulated Hi, as well as non-capsulated strains are known to cause a number of significant infections. Recognizing and understanding the links between the phenotypic traits and the genetic background has paramount epidemiological and clinical importance. To date, a panoply of microbiological and molecular biology tools have been developed and utilized by researchers aimed at identifying the evolutionary links among strains and isolates. Comparative genomic hybridization (CGH) has been shown to be a useful tool for screening strains for their genetic content. However, there is a major limitation when CGH is conducted on a microarray based on a single reference genome. CGH results report which genes are present or absent relative to the genome. Hence the information about novel genetic content that the query strain possesses remains obscure. We report here the construction of the first Hi pan-genome microarray representing ca. 4600 features by 70-mers. In addition to those from the Rd strain, new features originate from the unfinished genome sequences present in NCBI database and from our novel gene discovery project efforts using strain HK1212. Genomes of 20 strains belonging to different phylogenetic lineages were screened for their gene loss and gain utilizing the species microarray.
15 GSM201582 HI_119749_HK367Cy5_KW20Cy3_new_MDS.mev.refIsIA.out 32,448 The J. Craig Venter Institute 2007-06-15 [オリゴアレイ] JCVI PFGRC Haemophilus influenzae 32K vt1 array designed primarily based on strain HK12 [FULL_FEATURE_LAYOUT] (GPL5328) genomic インフルエンザ菌(Haemophilus influenzae)
Haemophilus influenzae
骨格筋 Haemophilus influenzae(Hi) is a gram-negative rod shaped bacterium that lives symbiotically in the upper respiratory tract of humans. Capsulated Hi, as well as non-capsulated strains are known to cause a number of significant infections. Recognizing and understanding the links between the phenotypic traits and the genetic background has paramount epidemiological and clinical importance. To date, a panoply of microbiological and molecular biology tools have been developed and utilized by researchers aimed at identifying the evolutionary links among strains and isolates. Comparative genomic hybridization (CGH) has been shown to be a useful tool for screening strains for their genetic content. However, there is a major limitation when CGH is conducted on a microarray based on a single reference genome. CGH results report which genes are present or absent relative to the genome. Hence the information about novel genetic content that the query strain possesses remains obscure. We report here the construction of the first Hi pan-genome microarray representing ca. 4600 features by 70-mers. In addition to those from the Rd strain, new features originate from the unfinished genome sequences present in NCBI database and from our novel gene discovery project efforts using strain HK1212. Genomes of 20 strains belonging to different phylogenetic lineages were screened for their gene loss and gain utilizing the species microarray.
16 GSM201583 HI_119750_2067Cy5_KW20Cy3_new_MDS.mev.refIsIA.out 32,448 The J. Craig Venter Institute 2007-06-15 [オリゴアレイ] JCVI PFGRC Haemophilus influenzae 32K vt1 array designed primarily based on strain HK12 [FULL_FEATURE_LAYOUT] (GPL5328) genomic インフルエンザ菌(Haemophilus influenzae)
Haemophilus influenzae
骨格筋 Haemophilus influenzae(Hi) is a gram-negative rod shaped bacterium that lives symbiotically in the upper respiratory tract of humans. Capsulated Hi, as well as non-capsulated strains are known to cause a number of significant infections. Recognizing and understanding the links between the phenotypic traits and the genetic background has paramount epidemiological and clinical importance. To date, a panoply of microbiological and molecular biology tools have been developed and utilized by researchers aimed at identifying the evolutionary links among strains and isolates. Comparative genomic hybridization (CGH) has been shown to be a useful tool for screening strains for their genetic content. However, there is a major limitation when CGH is conducted on a microarray based on a single reference genome. CGH results report which genes are present or absent relative to the genome. Hence the information about novel genetic content that the query strain possesses remains obscure. We report here the construction of the first Hi pan-genome microarray representing ca. 4600 features by 70-mers. In addition to those from the Rd strain, new features originate from the unfinished genome sequences present in NCBI database and from our novel gene discovery project efforts using strain HK1212. Genomes of 20 strains belonging to different phylogenetic lineages were screened for their gene loss and gain utilizing the species microarray.
17 GSM201584 HI_119891_HK368Cy5_KW20Cy3_new_MDS.mev.refIsIA.out 32,448 The J. Craig Venter Institute 2007-06-15 [オリゴアレイ] JCVI PFGRC Haemophilus influenzae 32K vt1 array designed primarily based on strain HK12 [FULL_FEATURE_LAYOUT] (GPL5328) genomic インフルエンザ菌(Haemophilus influenzae)
Haemophilus influenzae
骨格筋 Haemophilus influenzae(Hi) is a gram-negative rod shaped bacterium that lives symbiotically in the upper respiratory tract of humans. Capsulated Hi, as well as non-capsulated strains are known to cause a number of significant infections. Recognizing and understanding the links between the phenotypic traits and the genetic background has paramount epidemiological and clinical importance. To date, a panoply of microbiological and molecular biology tools have been developed and utilized by researchers aimed at identifying the evolutionary links among strains and isolates. Comparative genomic hybridization (CGH) has been shown to be a useful tool for screening strains for their genetic content. However, there is a major limitation when CGH is conducted on a microarray based on a single reference genome. CGH results report which genes are present or absent relative to the genome. Hence the information about novel genetic content that the query strain possesses remains obscure. We report here the construction of the first Hi pan-genome microarray representing ca. 4600 features by 70-mers. In addition to those from the Rd strain, new features originate from the unfinished genome sequences present in NCBI database and from our novel gene discovery project efforts using strain HK1212. Genomes of 20 strains belonging to different phylogenetic lineages were screened for their gene loss and gain utilizing the species microarray.
18 GSM201585 HI_119894_HK61Cy5_KW20Cy3_new_MDS.mev.refIsIA.out 32,448 The J. Craig Venter Institute 2007-06-15 [オリゴアレイ] JCVI PFGRC Haemophilus influenzae 32K vt1 array designed primarily based on strain HK12 [FULL_FEATURE_LAYOUT] (GPL5328) genomic インフルエンザ菌(Haemophilus influenzae)
Haemophilus influenzae
骨格筋 Haemophilus influenzae(Hi) is a gram-negative rod shaped bacterium that lives symbiotically in the upper respiratory tract of humans. Capsulated Hi, as well as non-capsulated strains are known to cause a number of significant infections. Recognizing and understanding the links between the phenotypic traits and the genetic background has paramount epidemiological and clinical importance. To date, a panoply of microbiological and molecular biology tools have been developed and utilized by researchers aimed at identifying the evolutionary links among strains and isolates. Comparative genomic hybridization (CGH) has been shown to be a useful tool for screening strains for their genetic content. However, there is a major limitation when CGH is conducted on a microarray based on a single reference genome. CGH results report which genes are present or absent relative to the genome. Hence the information about novel genetic content that the query strain possesses remains obscure. We report here the construction of the first Hi pan-genome microarray representing ca. 4600 features by 70-mers. In addition to those from the Rd strain, new features originate from the unfinished genome sequences present in NCBI database and from our novel gene discovery project efforts using strain HK1212. Genomes of 20 strains belonging to different phylogenetic lineages were screened for their gene loss and gain utilizing the species microarray.
19 GSM201587 HI_120118_KW20_self_self_new_MDS.mev.refIsIA.out 32,448 The J. Craig Venter Institute 2007-06-15 [オリゴアレイ] JCVI PFGRC Haemophilus influenzae 32K vt1 array designed primarily based on strain HK12 [FULL_FEATURE_LAYOUT] (GPL5328) genomic インフルエンザ菌(Haemophilus influenzae)
Haemophilus influenzae
骨格筋 Haemophilus influenzae(Hi) is a gram-negative rod shaped bacterium that lives symbiotically in the upper respiratory tract of humans. Capsulated Hi, as well as non-capsulated strains are known to cause a number of significant infections. Recognizing and understanding the links between the phenotypic traits and the genetic background has paramount epidemiological and clinical importance. To date, a panoply of microbiological and molecular biology tools have been developed and utilized by researchers aimed at identifying the evolutionary links among strains and isolates. Comparative genomic hybridization (CGH) has been shown to be a useful tool for screening strains for their genetic content. However, there is a major limitation when CGH is conducted on a microarray based on a single reference genome. CGH results report which genes are present or absent relative to the genome. Hence the information about novel genetic content that the query strain possesses remains obscure. We report here the construction of the first Hi pan-genome microarray representing ca. 4600 features by 70-mers. In addition to those from the Rd strain, new features originate from the unfinished genome sequences present in NCBI database and from our novel gene discovery project efforts using strain HK1212. Genomes of 20 strains belonging to different phylogenetic lineages were screened for their gene loss and gain utilizing the species microarray.
20 GSM201653 HI_120540_KW20_self_self_new_MDS.mev.refIsIA.out 32,448 The J. Craig Venter Institute 2007-06-15 [オリゴアレイ] JCVI PFGRC Haemophilus influenzae 32K vt1 array designed primarily based on strain HK12 [FULL_FEATURE_LAYOUT] (GPL5328) genomic インフルエンザ菌(Haemophilus influenzae)
Haemophilus influenzae
骨格筋 Haemophilus influenzae(Hi) is a gram-negative rod shaped bacterium that lives symbiotically in the upper respiratory tract of humans. Capsulated Hi, as well as non-capsulated strains are known to cause a number of significant infections. Recognizing and understanding the links between the phenotypic traits and the genetic background has paramount epidemiological and clinical importance. To date, a panoply of microbiological and molecular biology tools have been developed and utilized by researchers aimed at identifying the evolutionary links among strains and isolates. Comparative genomic hybridization (CGH) has been shown to be a useful tool for screening strains for their genetic content. However, there is a major limitation when CGH is conducted on a microarray based on a single reference genome. CGH results report which genes are present or absent relative to the genome. Hence the information about novel genetic content that the query strain possesses remains obscure. We report here the construction of the first Hi pan-genome microarray representing ca. 4600 features by 70-mers. In addition to those from the Rd strain, new features originate from the unfinished genome sequences present in NCBI database and from our novel gene discovery project efforts using strain HK1212. Genomes of 20 strains belonging to different phylogenetic lineages were screened for their gene loss and gain utilizing the species microarray.
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